Mental health and miscarriage risk linked?

Mother’s Mental Health Associated with Miscarriage Risk

For some women, pregnancy is not a happy journey as complications slip in either during pregnancy or delivery. The chances of a complication increase if an expecting mother has diabetes, heart disease or HIV/AIDS. Also, researchers established a link between a relapsing autoimmune disorder and the risk of miscarriage. According to the new study (published online in Neurology), women suffering from neuromyelitis optica spectrum disorder (NMOSD) are likely to have higher odds of miscarriage and pre-eclampsia during pregnancy, particularly, the pregnancies that occur three years before or after the disease starts.

NMOSD mainly affects the optic nerves and the spinal cord which can cause sudden vision loss or weakness in one or both eyes. It can also affect parts of the brain in some cases. Currently, there are not many treatment options available to combat the disease, though immunosuppressive drugs have proven to be effective against severe attacks and also prevent the disorder from relapsing. The scientists are working on new molecularly targeted drugs for the treatment of NMOSD. The disorder is sometimes confused with multiple sclerosis (MS). The disease modifying drugs for MS can sometimes adversely affect people suffering from NMOSD. Thus, early diagnosis is extremely essential.

To study the NMOSD-miscarriage relationship, a team of researchers assigned a questionnaire to 60 women with the severe recurrent antibody mediated inflammatory disorder of the central nervous system (CNS). A total of 126 pregnancies, before or after the onset of the condition, were documented in the study. The research showed a high rate of miscarriage in the participants. The authors noted that 11 pregnancies in 6 women ended in miscarriage. Six of 14 pregnancies after NMOSD onset caused spontaneous abortion and 5 of 71 pregnancies leading to the same were reported before the onset.

In addition to this, pregnant woman suffering from multiple other autoimmune diseases were found at an increased 11.5% risk of pre-eclampsia. According to the researchers, the proportion is considerably higher than the control population (nearly 3%).

Source : Health Daily Digest (via Syndication)

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